产品货号:
Z12857
中文名称:
CD43/SPN抗体
英文名称:
Anti-CD43/SPN Antibody
产品规格:
50μl|100μl|150μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-CD43/SPN Antibody |
指标别名 | CD43;Galactoglycoprotein;GALGP;GPL115;Leukocyte sialoglycoprotein;Leukosialin;LSN;sialophorin;SPN |
克隆性 | Polyclonal |
检验物种 | human,mouse,rat |
应用范围 | WB,IHC,IHC-F,IF,ICC,FCM |
基因名称 | SPN |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | E.coli-derived human CD43 recombinant protein (Position:A272-P400).Human CD43 shares 72% and 73% amino acid (aa) sequences identity with mouse and rat CD43,respectively. |
实际分子量 | 100~120KD |
成分 | 500μg/mL antibody with PBS,0.02% NaN3,1mg BSA and 50% glycerol. |
纯化方式 | Immunogen affinity purified. |
浓度 | 500μg/mL |
产品形态 | 溶液 |
保存条件 | 12 months from date of receipt,-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
背景资料 | CD43,also known as leukosialin or sialophorin,is a transmembrane cell surface protein that in humans is encoded by the SPN gene.It is mapped to 16p11.2.It is a major sialoglycoprotein on the surface of human T lymphocytes,monocytes,granulocytes,and some B lymphocytes,which is important for immune function and may be part of a physiologic ligand-receptor complex involved in T-cell activation.Expression of CD43 is deficient and/or defective in the X-chromosome-linked immunodeficiency disorder Wiscott-Aldrich syndrome,suggesting that CD43 have a role in T-cell activation.T-cell activation requires the removal of CD43 from the immunologic synapse to allow efficient engagement of the TCR with molecules on the APC. |
Uniprot ID | P16150 |
推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
基因名全称 | sialophorin |
蛋白名全称 | Leukosialin |
推荐稀释比 | Western blot(WB) 1:500~2000 Immunohistochemistry in paraffin section (IHC) 1:50~400 Immunohistochemistry in frozen section (IHC-F) 1:50~400 Immunocytochemistry 1:50~400 Immunofluorescence (IF) 1:50~400 Flow cytometry (FCM) 1~3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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